Abstract. The paper presents literature and research data about epidemiology and disease course of microsporia and dermatophytosis. The main causative agents of microsporia is - M. canis, of dermatophytosis are – Tr. mentagrophytesvar. gypseum, Tr. Violaceum, Tr. Tonsurans, Tr. Verrucosum. Atypical disease course often found at present time. Newborns and adults more often suffer from these diseases.